VEGF和MVD在正常对照组与病例组及肿瘤Dukes分期各期之间、病理分级各级之间均有统计学意义且VEGF与MVD两者之间存在着明显的正相关关系说明新生微血管的生成在大肠癌的发生、发展过程中起着重要的作用血管生成亦是具有独立判断预后作用的标记物。而VEGF在调节大肠癌微血管生成方面可能起主要的调节作用。参考文献1LamszusKHeeseOWestphalMA
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