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重组人血小板生成素联合地塞米松治疗原发免疫性血小板减少症的疗效探讨
作者:胡晓萍来源:《中国实用医药》2017年第09期
【摘要】目的探讨重组人血小板生成素联合地塞米松治疗原发免疫性血小板减少症的临床疗效。方法64例原发免疫性血小板减少症患者,将其随机分成对照组和观察组,每组32例。对照组患者使用地塞米松治疗,观察组患者使用重组人血小板生成素联合地塞米松治疗。比较两组治疗效果。结果治疗后,观察组血小板计数为(1328±656)×109L,高于对照组的(768±685)×109L,差异有统计学意义(P005)。结论重组人血小板生成素联合地塞米松治疗原发免疫性血小板减少症疗效显著,无明显副作用,可在临床推广用。【关键词】重组人血小板生成素;地塞米松;原发免疫性血小板减少症;疗效DOI:1014163jc
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ia;Curativeeffect原发免疫性血小板减少症是以循环血小板减少和出血风险增加为特征的血液系统疾病,占出血性疾病的13,有着较高的致死率1。正常生理条件下血小板减少时血小板生成素随之增加,但该类患者的血小板生成素不会随之变化2,无法形成弥补性机制。目前临床治疗血小板减少症的主要药物是糖皮质激素,促血小板生成素近年也被应用到该病治疗当中,本研
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