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comc
知柏地黄丸联合醋酸曲普瑞林治疗儿童中枢
性性早熟疗效分析
作者:王颖刘京霞杨坤李荣敏赵永辰来源:《健康周刊》2018年第03期
【摘要】目的:探讨对儿童中枢性性早熟患儿采用知柏地黄丸联合醋酸曲普瑞林治疗的疗效。方法:选择2015年3月至2017年1月我院就诊的中枢性性早熟CPP女童76例为研究对象。分为对照组40例采用醋酸曲普瑞林治疗,治疗组36例在对照组的基础上采用知柏地黄丸口服,连续治疗6个月。比较2组治疗后治疗组和对照组身高的标准差计数(HtSDS)、生长速度(cm6个月)、胰岛素样生长因子1(IGF1)、促卵泡生成素(FSH)、黄体生成素(LH)和雌二醇(E2)。结果:治疗组患者的性激素水平、生长参数均较对照组降低,其中治疗组生长速度、LH显著优于对照组患者,P
【关键词】知柏地黄丸;中枢性性早熟;醋酸曲普瑞林
Cli
icalobservatio
ofZhibaiDihua
gPillscombi
edwithtriptoreli
acetatei
treatme
tofchildre
ce
tralprecociouspuberty
【Abstract】Objective:Toi
vestigatethecli
icaleffectofZhibaiDihua
gPillscombi
edwithtriptoreli
acetatei
treatme
tofchildre
ce
tralprecociouspubertyMethods:Childre
(76cases)withce
tralprecociouspubertyi
Baodi
gChildre
’sHospitalfromMarch2015toJa
uary2017weredividedi
totheco
trolgroupwiththetreatme
toftriptoreli
acetate(40cases)a
dtreatme
tgroupcombi
edwiththetreatme
toftriptoreli
acetatea
dZhibaiDihua
gPills(36cases)accordi
gtodiffere
ttreatme
tThediag
osticcriteriaisuptodiag
osisa
dtreatme
tguideli
es(o
trail)whichispublishedbyMi
istryofHealth2010Comparethetwogroups’dataofsta
darddeviatio
,growthrate(cm6mo
th),(FSH),(LH)a
d(E2)Results:Aftertreatme
t,growthratei
thetreatme
tgroupwerelowertha
thosei
theco
trolgroup,withsig
ifica
tdiffere
cebetwee
twogroups(P005)Aftertreatme
t,LHleveli
twogroupswassig
ifica
tlydecreased,a
dtherewerediffere
cesbetwee
twogroups(P005)co
clusio
:theresearchshowsthatthegroupwiththetreatme
toftriptoreli
acetatea
dZhibaiDihua
gPillshasa
sig
ifica
teffectThetreatme
tca
restrai
precocitysymptoma
dafterthefollowupvisit,thereis
’tu
towardeffectHowever,whetheritisworththecli
icalapplicatio
,ara
domizedco
trolledstudyofmultice
trea
dlargesamplesstill
eedtobeco
firmedi
thefuture
【Keywords】ZhibaiDihua
gPills;ce
tralprecociouspuberty;triptoreli
acetate
f龙源期刊网httpwwwqika
comc
中医学认为中枢性性早熟(ce
tralprecociouspuberty,CPP)因受到大量高激素食物、营养过剩及膏粱厚味等因素影响,性早熟r
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