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comc
尿蛋白肌酐、24h尿蛋白及肾功能指标检测在慢性肾病诊断中的价值
作者:陈吉虎来源:《医学信息》2019年第17期
摘要:目的探讨检测尿蛋白肌酐(UpCr)、24h尿蛋白(24hUp)及肾功能检测在慢性肾病诊断中的价值。方法选取2017年9月~2018年12月我院收治的慢性肾病患者526例,根据肌酐清除率(Ccr)分为肾功能正常组100例、轻度损害组105例、中度损害组105例、重度损害组108例和尿毒症组108例。比较五组血肌酐(Scr)、UpCr、24hUp水平,并分析UpCr和24hUp的相关性。结果中度、重度损害组和尿毒症组Scr高于肾功能正常组和轻度损害组,差异有统计学意义(P005)。轻度、中度、重度损害组、尿毒症组UpCr高于肾功能正常组,轻度、中度、重度损害组、尿毒症组24hUp高于肾功能正常组,差异有统计学意
f龙源期刊网httpwwwqika
comc
义(P005)。结论UPCr和24hUP早期诊断慢性肾病效果优于Scr,当Ccr超过了10mlmi
时,其可用于临床慢性肾病的早期筛检。
关键词:尿蛋白肌酐24h尿蛋白慢性肾病肾功能
Abstract:ObjectiveToi
vestigatethevalueofuri
eprotei
creati
i
e(UpCr),24huri
eprotei
(24hUp)a
dre
alfu
ctio
testi
thediag
osisofchro
ickid
eydiseaseMethodsAtotalof526patie
tswithchro
ickid
eydiseaseadmittedtoourhospitalfromSeptember2017toDecember2018weree
rolledAccordi
gtocreati
i
ecleara
cerate(Ccr),therewere100patie
tswith
ormalre
alfu
ctio
,105patie
tswithmildi
jury,a
d105patie
tswithmoderatedamage108patie
tsi
theseverei
jurygroupa
d108patie
tsi
theuremicgroup5groupsofserumcreati
i
e(Scr),UpCr,a
d24hUplevelswerecompared,a
dthecorrelatio
betwee
UpCra
d24hUpwasa
alyzedResultsTheScrofthemoderate,severei
jurygroupa
duremicgroupwashighertha
thatofthe
ormalre
alfu
ctio
groupa
dthemilddamagegroup(P005)Therewas
osig
ifica
tdiffere
cei
theScrbetwee
the
ormalre
alfu
ctio
groupa
dthemildi
jurygroup(P005)I
themild,moderate,severelesio
groupsa
dtheuremiagroup,theUpCrgroupwashighertha
the
ormalre
alfu
ctio
groupmild,moderate,severei
jurygroups,uremiagroup24hUpwashighertha
ormalre
alfu
ctio
group,thehighesti
themoderatedamagegroup,thediffere
cewasstatisticallysig
ifica
t(P005)Therewasacorrelatio
betwee
UpCra
d24hUpi
the
ormalre
alfu
ctio
group,mild,moderategroupa
dtheseveredamagegroups(P005)Therewas
ocorrelatio
betwee
UpCra
d24hUpi
theuremicgroup(P005)Co
clusio
Theearlydiag
osisofchro
ickid
eydiseasebyUPCra
d24hUPisbettertha
Scrr