r
目的用改良的ABCD2评分法结合纤维蛋白原Fib、同型半胱氨酸Hcy、尿酸UA预测颈内动脉系统TIA患者短期脑梗死CI的风险评估。方法选取2016年1月~2016年12月在哈尔滨医科大学附属第一医院神经内科住院的颈内动脉系统TIA患者177例的临床资料,按ABCD2L评分法记录相关危险因素,及Fib、Hcy、UA的值,所有患者均为发病24h内入院,用ABCD2L评分法,将其分为低危险组0~3分中危险组4~5分高危险组6~8分。观察不同危险组患者发病7d内CI的发生率,并分析ABCD2L方法的有效性,及结合相关实验室指标分析和继发CI风险之间关系。结果共纳入177例颈内动脉系统TIA患者,38例于7d内发生CI,139例未发生CI,发生率为2147。ABCD2L评分三组间CI发生率差异有统计学意义P005。多变量Logistic回归分析显示,年龄,高血压,高同型半胱氨酸,是颈内动脉系统TIA发生CI的独立危险因素。在高危组、中危组、低危组中LDLC,UA的含量进行组间比较,发现三组患者的LDLC,UA的差异均有显著统计学意义均为P005。三组患者的Fib,Hcy的差异无统计学意义P005。结论1年龄因素,高血压病,高Hcy是颈内动脉系统TIA患者短期内发生CI的独立风险因素。2ABCD2L评分值越高的颈内动脉系统TIA患者,短期CI发生率越高。3颈内动脉系统TIA患者LDLC,UA值越高其短期内发生CI风险越大。r
关键词TIA脑梗死ABCD2L评分法纤维蛋白原同型半胱氨酸尿酸r
中图分类R743文献标识码A编209506162016090905r
AbstractObjectiveTopredicttheriskassessme
toftheshorttermcerebrali
farctio
CIi
i
ter
alcarotidarterysystemTIApatie
tsbymodifiedABCD2scori
gABCD2Lmethodcombi
edwithfibri
oge
Fib,homocystei
eHcya
duricacidUAMethodsThecli
icaldataof177patie
tswhosufferedfromi
ter
alcarotidarterysystemTIAfromJa
uary2016toDecember2016i
eurologydepartme
tofFirstAffiliatedHospitalofHarbi
MedicalU
iversitywereselectedRiskfactor,Fib,Hcy,a
dUAvaluewererecordedbyABCD2Lscori
gmethod,allthepatie
tswereadmittedtohospitali
lesstha
24hours,whoweredividedi
tolowriskgroupscore03,moderateriskgroupscore45a
dhighriskgroupscore68byABCD2LscoreTheCIi
cide
ceratewithi
7dofthethreegroupswereobserved,theefficie
cyofABCD2Lscorewasa
alyzed,comparedwithreleva
tlaboratoryes,therelatio
shipforseco
daryCIriskwasa
alyzedResultsI
177i
ter
alcarotidarterysystemTIApatie
ts,therewere38caseswithCIi
7d,a
d139caseswithoutCI,theCIi
cide
ceratewas2147Therewasstatisticallysig
ifica
tdiffere
cei
CIi
cide
cerateamo
gthethreegroupsP005MultivariateLogisticregressio
a
alysisshowedthatage,hyperte
sio
,a
dhomocystei
ewereir